{"id":932,"date":"2026-10-14T04:47:42","date_gmt":"2026-10-14T04:47:42","guid":{"rendered":"https:\/\/kdoctorinterview.com\/?p=932"},"modified":"2026-10-14T04:47:45","modified_gmt":"2026-10-14T04:47:45","slug":"%ec%9c%84%ea%b3%a0%eb%b9%84-%eb%a7%88%ec%9a%b4%ec%9e%90%eb%a1%9c-%ec%8b%9c%eb%8c%80-%eb%81%9d-%eb%a8%b9%eb%8a%94-%eb%b9%84%eb%a7%8c%ec%b9%98%eb%a3%8c%ec%a0%9c-%ed%8c%8c%ec%9a%b4%eb%8b%a4%ec%9a%94","status":"publish","type":"post","link":"https:\/\/kdoctorinterview.com\/vi\/%ec%9c%84%ea%b3%a0%eb%b9%84-%eb%a7%88%ec%9a%b4%ec%9e%90%eb%a1%9c-%ec%8b%9c%eb%8c%80-%eb%81%9d-%eb%a8%b9%eb%8a%94-%eb%b9%84%eb%a7%8c%ec%b9%98%eb%a3%8c%ec%a0%9c-%ed%8c%8c%ec%9a%b4%eb%8b%a4%ec%9a%94\/","title":{"rendered":"K\u1ef7 nguy\u00ean Wegovy v\u00e0 Mounjaro s\u1eafp k\u1ebft th\u00fac? Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u00e9o ph\u00ec d\u1ea1ng u\u1ed1ng m\u1edbi \u201cPoundaio\u201d th\u1ef1c ch\u1ea5t l\u00e0 g\u00ec?"},"content":{"rendered":"
\"\"<\/figure>\n\n\n\n

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G\u1ea7n \u0111\u00e2y, c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u00e9o ph\u00ec d\u1ea1ng ti\u00eam nh\u01b0 Wegovy v\u00e0 Mounjaro \u0111\u00e3 tr\u1edf n\u00ean r\u1ea5t ph\u1ed5 bi\u1ebfn. Tuy nhi\u00ean, vi\u1ec7c ph\u1ea3i t\u1ef1 ti\u00eam h\u1eb1ng tu\u1ea7n, chi ph\u00ed cao v\u00e0 nh\u1eefng h\u1ea1n ch\u1ebf trong chu\u1ed7i b\u1ea3o qu\u1ea3n l\u1ea1nh \u0111\u00e3 khi\u1ebfn kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn c\u00e1c thu\u1ed1c n\u00e0y c\u00f2n th\u1ea5p.<\/p>\n\n\n\n

M\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nh\u1eb1m kh\u1eafc ph\u1ee5c nh\u1eefng h\u1ea1n ch\u1ebf n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c FDA Hoa K\u1ef3 ph\u00ea duy\u1ec7t v\u00e0o th\u00e1ng 4 n\u0103m 2026. Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u00e9o ph\u00ec d\u1ea1ng u\u1ed1ng m\u1edbi \u201cPoundaio\u201d (ho\u1ea1t ch\u1ea5t: Orforglipron)<\/mark><\/em><\/strong>Lo\u1ea1i thu\u1ed1c m\u1edbi n\u00e0y \u0111ang nh\u1eadn \u0111\u01b0\u1ee3c r\u1ea5t nhi\u1ec1u s\u1ef1 quan t\u00e2m. Ch\u00fang ta s\u1ebd c\u00f9ng ph\u00e2n t\u00edch chi ti\u1ebft s\u1ef1 kh\u00e1c bi\u1ec7t c\u1ee7a n\u00f3 so v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7n c\u00f3, nh\u1eefng hi\u1ec7u qu\u1ea3 ti\u1ec1m n\u0103ng v\u00e0 c\u01a1 ch\u1ebf khoa h\u1ecdc \u0111\u1ee9ng sau t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c.<\/p>\n\n\n\n

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1. S\u1ef1 ti\u1ebfn h\u00f3a c\u1ee7a thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u00e9o ph\u00ec: T\u1eeb thu\u1ed1c ti\u00eam GLP-1 \u0111\u1ebfn thu\u1ed1c u\u1ed1ng<\/h3>\n<\/blockquote>\n\n\n\n
    \n
  • T\u1ea1i sao ch\u00fang ta t\u0103ng c\u00e2n?<\/strong>\u00a0: Khi \u0103n, trong ru\u1ed9t...\u00a0Hormone GLP-1<\/strong>Hormone n\u00e0y \u0111\u01b0\u1ee3c ti\u1ebft ra v\u00e0 g\u1eedi t\u00edn hi\u1ec7u no \u0111\u1ebfn n\u00e3o b\u1ed9, nh\u01b0ng \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb b\u00e9o ph\u00ec, s\u1ef1 ti\u1ebft hormone n\u00e0y gi\u1ea3m \u0111i v\u00e0 c\u01a1 ch\u1ebf \u201cphanh\u201d c\u1ea3m gi\u00e1c no tr\u1edf n\u00ean k\u00e9m nh\u1ea1y h\u01a1n.<\/li>\n\n\n\n
  • S\u1ef1 ra \u0111\u1eddi c\u1ee7a c\u00e1c li\u1ec7u ph\u00e1p d\u1ea1ng ti\u00eam<\/strong>\u00a0: Wegovy (semaglutide) c\u1ee7a Novo Nordisk l\u00e0 thu\u1ed1c ti\u00eam \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n b\u1eb1ng c\u00e1ch bi\u1ebfn \u0111\u1ed5i c\u1ea5u tr\u00fac c\u1ee7a GLP-1, v\u1ed1n th\u01b0\u1eddng b\u1ecb ph\u00e2n h\u1ee7y nhanh trong c\u01a1 th\u1ec3, gi\u00fap thu\u1ed1c duy tr\u00ec t\u00e1c d\u1ee5ng l\u00e2u h\u01a1n. C\u00f2n thu\u1ed1c c\u1ee7a Eli Lilly...\u00a0Mounjaro<\/strong>Thu\u1ed1c c\u1ee7a Eli Lilly t\u1ea1o ra hi\u1ec7u qu\u1ea3 gi\u1ea3m c\u00e2n l\u1edbn h\u01a1n b\u1eb1ng c\u00e1ch k\u00edch th\u00edch \u0111\u1ed3ng th\u1eddi c\u1ea3 hai th\u1ee5 th\u1ec3 GLP-1 v\u00e0 GIP.<\/li>\n\n\n\n
  • Nh\u1eefng h\u1ea1n ch\u1ebf v\u00e0 th\u00e1ch th\u1ee9c c\u1ee7a thu\u1ed1c u\u1ed1ng<\/strong>\u00a0: C\u00e1c thu\u1ed1c u\u1ed1ng d\u1ef1a tr\u00ean peptide (protein) c\u00f3 h\u1ea1n ch\u1ebf l\u00e0 d\u1ec5 b\u1ecb ph\u00e2n h\u1ee7y b\u1edfi axit d\u1ea1 d\u00e0y v\u00e0 c\u00e1c enzym ti\u00eau h\u00f3a, v\u00ec v\u1eady \u0111\u1ec3 \u0111\u01b0\u1ee3c h\u1ea5p thu hi\u1ec7u qu\u1ea3, ng\u01b0\u1eddi d\u00f9ng ph\u1ea3i tu\u00e2n th\u1ee7 c\u00e1c quy tr\u00ecnh nghi\u00eam ng\u1eb7t nh\u01b0 u\u1ed1ng khi \u0111\u00f3i c\u00f9ng v\u1edbi 120 mL n\u01b0\u1edbc.<\/li>\n\n\n\n
  • <\/li>\n<\/ul>\n\n\n\n
    \n

    Ph\u00e2n t\u1eed nh\u1ecf kh\u00f4ng ph\u1ea3i peptide<\/h3>\n<\/blockquote>\n\n\n\n
      \n
    • \u201cChi\u1ebfc ch\u00eca kh\u00f3a\u201d m\u1edbi \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p h\u00f3a h\u1ecdc<\/strong>\u00a0: Ho\u1ea1t ch\u1ea5t c\u1ee7a Poundaio l\u00e0 orforglipron,\u00a0Orforglipron<\/strong>Orforglipron kh\u00f4ng ph\u1ea3i l\u00e0 protein (peptide), m\u00e0 l\u00e0 m\u1ed9t h\u1ee3p ch\u1ea5t \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p h\u00f3a h\u1ecdc\u00a0Ph\u00e2n t\u1eed nh\u1ecf kh\u00f4ng ph\u1ea3i peptide<\/strong>l\u00e0.<\/li>\n\n\n\n
    • C\u1ea5u tr\u00fac b\u1ec1n v\u1eefng tr\u01b0\u1edbc axit d\u1ea1 d\u00e0y<\/strong>\u00a0: Kh\u00e1c v\u1edbi nh\u1eefng \u201cchi\u1ebfc ch\u00eca kh\u00f3a\u201d truy\u1ec1n th\u1ed1ng m\u00f4 ph\u1ecfng tr\u1ef1c ti\u1ebfp hormone t\u1ef1 nhi\u00ean, \u0111\u00e2y l\u00e0 m\u1ed9t \u201cchi\u1ebfc ch\u00eca kh\u00f3a\u201d m\u1edbi \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf t\u1eeb \u0111\u1ea7u sau khi ph\u00e2n t\u00edch c\u1ea5u tr\u00fac c\u1ee7a \u201c\u1ed5 kh\u00f3a\u201d, v\u00ec v\u1eady kh\u00f4ng b\u1ecb ph\u00e2n h\u1ee7y b\u1edfi axit d\u1ea1 d\u00e0y. Do \u0111\u00f3, thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng m\u00e0 kh\u00f4ng c\u1ea7n ch\u1ea5t t\u0103ng h\u1ea5p thu \u0111\u1eb7c bi\u1ec7t (SNAC) hay ch\u1ebf \u0111\u1ed9 u\u1ed1ng thu\u1ed1c l\u00fac \u0111\u00f3i nghi\u00eam ng\u1eb7t.\u00a0C\u00f3 th\u1ec3 d\u00f9ng d\u1ec5 d\u00e0ng b\u1ea5t c\u1ee9 l\u00fac n\u00e0o<\/strong>C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng d\u1ec5 d\u00e0ng v\u00e0o b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o.<\/li>\n<\/ul>\n\n\n\n

      <\/p>\n\n\n\n

      \"\"<\/figure>\n\n\n\n
      \n

      So s\u00e1nh hi\u1ec7u qu\u1ea3, t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 gi\u00e1 th\u00e0nh<\/h3>\n<\/blockquote>\n\n\n\n
        \n
      • Hi\u1ec7u qu\u1ea3 gi\u1ea3m c\u00e2n<\/strong>\u00a0: Theo k\u1ebft qu\u1ea3 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ATTAIN, khi s\u1eed d\u1ee5ng li\u1ec1u cao nh\u1ea5t (36 mg) trong 72 tu\u1ea7n,\u00a0C\u00e2n n\u1eb7ng trung b\u00ecnh gi\u1ea3m 12,4%<\/strong>M\u1eb7c d\u00f9 con s\u1ed1 n\u00e0y c\u00f3 th\u1ec3 th\u1ea5p h\u01a1n so v\u1edbi Wegovy (kho\u1ea3ng 15%) ho\u1eb7c Mounjaro\/Zepbound (kho\u1ea3ng 20%), nh\u01b0ng kh\u00f4ng th\u1ec3 so s\u00e1nh tr\u1ef1c ti\u1ebfp v\u1edbi Wegovy d\u1ea1ng u\u1ed1ng (16,6%) do s\u1ef1 kh\u00e1c bi\u1ec7t v\u1ec1 nh\u00f3m b\u1ec7nh nh\u00e2n v\u00e0 \u0111i\u1ec1u ki\u1ec7n th\u1eed nghi\u1ec7m.<\/li>\n\n\n\n
      • So s\u00e1nh tr\u00ean b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/strong>\u00a0: Trong th\u1eed nghi\u1ec7m ACHIEVE 3 (thu\u1ed9c nh\u00f3m SURPASS\/ACHIEVE), khi so s\u00e1nh trong 52 tu\u1ea7n \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00edp 2, Poundaio 36 mg cho k\u1ebft qu\u1ea3 v\u01b0\u1ee3t tr\u1ed9i h\u01a1n Wegovy d\u1ea1ng u\u1ed1ng 14 mg \u1edf c\u1ea3 kh\u1ea3 n\u0103ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 gi\u1ea3m c\u00e2n.<\/li>\n\n\n\n
      • Hi\u1ec7u qu\u1ea3 kinh t\u1ebf v\u00e0 s\u1ef1 thu\u1eadn ti\u1ec7n trong ph\u00e2n ph\u1ed1i<\/strong>\u00a0: T\u1ea1i M\u1ef9, chi ph\u00ed b\u1eaft \u0111\u1ea7u t\u1eeb 25 USD\/th\u00e1ng (kho\u1ea3ng 34.000 won) n\u1ebfu \u0111\u01b0\u1ee3c b\u1ea3o hi\u1ec3m chi tr\u1ea3 v\u00e0 t\u1eeb 149 USD\/th\u00e1ng (kho\u1ea3ng 200.000 won) n\u1ebfu t\u1ef1 thanh to\u00e1n.\u00a0Kh\u00f4ng c\u1ea7n b\u1ea3o qu\u1ea3n l\u1ea1nh ho\u1eb7c v\u1eadn chuy\u1ec3n theo chu\u1ed7i l\u1ea1nh<\/strong>\u00a0Gi\u00fap gi\u1ea3m \u0111\u00e1ng k\u1ec3 chi ph\u00ed v\u00e0 r\u00e0o c\u1ea3n trong qu\u00e1 tr\u00ecnh ph\u00e2n ph\u1ed1i.<\/li>\n<\/ul>\n\n\n\n

        <\/p>\n\n\n\n

        \n

        Tri\u1ec3n v\u1ecdng ra m\u1eaft t\u1ea1i H\u00e0n Qu\u1ed1c<\/h3>\n<\/blockquote>\n\n\n\n
          \n
        • : V\u00e0o th\u1eddi \u0111i\u1ec3m \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t, Eli Lilly \u0111\u00e3 n\u1ed9p h\u1ed3 s\u01a1 xin c\u1ea5p ph\u00e9p t\u1ea1i h\u01a1n 40 qu\u1ed1c gia tr\u00ean th\u1ebf gi\u1edbi, v\u00e0 c\u00e1c b\u1ec7nh vi\u1ec7n t\u1ea1i H\u00e0n Qu\u1ed1c c\u0169ng tham gia v\u00e0o th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng to\u00e0n c\u1ea7u ATTAIN-2.<\/li>\n\n\n\n
        • X\u00e9t \u0111\u1ebfn vi\u1ec7c th\u1eddi gian th\u1ea9m \u0111\u1ecbnh thu\u1ed1c m\u1edbi c\u1ee7a B\u1ed9 An to\u00e0n Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m H\u00e0n Qu\u1ed1c (MFDS) trung b\u00ecnh kho\u1ea3ng 10 th\u00e1ng,\u00a0Trong kho\u1ea3ng t\u1eeb cu\u1ed1i n\u0103m 2026 \u0111\u1ebfn gi\u1eefa n\u0103m 2027<\/strong>D\u1ef1 ki\u1ebfn thu\u1ed1c s\u1ebd \u0111\u01b0\u1ee3c ra m\u1eaft t\u1ea1i H\u00e0n Qu\u1ed1c trong kho\u1ea3ng t\u1eeb cu\u1ed1i n\u0103m 2026 \u0111\u1ebfn gi\u1eefa n\u0103m 2027. Do l\u00e0 thu\u1ed1c ph\u00e2n t\u1eed nh\u1ecf, gi\u00e1 th\u00e0nh c\u1ee7a thu\u1ed1c \u0111\u01b0\u1ee3c k\u1ef3 v\u1ecdng s\u1ebd th\u1ea5p h\u01a1n so v\u1edbi c\u00e1c thu\u1ed1c d\u1ea1ng ti\u00eam.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

          \ucd5c\uadfc \uc704\uace0\ube44\uc640 \ub9c8\uc6b4\uc790\ub85c \ub4f1 \uc8fc\uc0ac\ud615 \ube44\ub9cc \uce58\ub8cc\uc81c\uac00 \ud070 \uc778\uae30\ub97c \ub04c\uace0 \uc788\uc9c0\ub9cc, \ub9e4\uc8fc \uc2a4\uc2a4\ub85c \uc8fc\uc0ac\ub97c \ub9de\uc544\uc57c \ud55c\ub2e4\ub294 \ubd80\ub2f4\uac10\uacfc \ub192\uc740 \uac00\uaca9, \ucf5c\ub4dc\uccb4\uc778 \uc720\ud1b5\uc758 \ud55c\uacc4 \ub4f1\uc73c\ub85c \uc811\uadfc\uc131\uc774 \ub0ae\uc558\ub358 \uac83\uc774 \uc0ac\uc2e4\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ub2e8\uc810\uc744 \uadf9\ubcf5\ud558\uace0 2026\ub144 4\uc6d4 \ubbf8\uad6d FDA \uc2b9\uc778\uc744 \ud1b5\uacfc\ud55c \uc0c8\ub85c\uc6b4 \uba39\ub294 \ube44\ub9cc \uce58\ub8cc\uc81c ‘\ud30c\uc6b4\ub2e4\uc774\uc624(\uc131\ubd84\uba85: \uc624\ud3ec\uae00\ub9ac\ud504\ub85c)’\uac00 \uc8fc\ubaa9\ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uae30\uc874 \uce58\ub8cc\uc81c\uc640 \ubb34\uc5c7\uc774 \ub2e4\ub974\uace0 \uc5b4\ub5a4 \ud6a8\uacfc\uac00 \uc788\ub294\uc9c0 \uacfc\ud559\uc801 \uc6d0\ub9ac\ub97c \ubc14\ud0d5\uc73c\ub85c \uc2f9 […]<\/p>\n","protected":false},"author":4,"featured_media":933,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[24],"tags":[],"class_list":["post-932","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-primary-health-care-provider"],"jetpack_featured_media_url":"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub9c8\uc6b4\uc790\ub85c.jpeg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/posts\/932","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/comments?post=932"}],"version-history":[{"count":1,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/posts\/932\/revisions"}],"predecessor-version":[{"id":936,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/posts\/932\/revisions\/936"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/media\/933"}],"wp:attachment":[{"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/media?parent=932"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/categories?post=932"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kdoctorinterview.com\/vi\/wp-json\/wp\/v2\/tags?post=932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}