{"id":926,"date":"2026-10-14T02:34:45","date_gmt":"2026-10-14T02:34:45","guid":{"rendered":"https:\/\/kdoctorinterview.com\/?p=926"},"modified":"2026-10-14T02:34:47","modified_gmt":"2026-10-14T02:34:47","slug":"%ea%b2%80%eb%b2%84%ec%84%af%ec%9d%b4-%ea%b0%91%ec%9e%90%ea%b8%b0-%eb%8a%98%ec%97%88%eb%8b%a4%eb%a9%b4-%ec%95%94-%ec%8b%a0%ed%98%b8%ec%9d%bc%ea%b9%8c-%eb%a0%88%ec%a0%9c%eb%a5%b4-%ed%8a%b8%eb%a0%90","status":"publish","type":"post","link":"https:\/\/kdoctorinterview.com\/en\/%ea%b2%80%eb%b2%84%ec%84%af%ec%9d%b4-%ea%b0%91%ec%9e%90%ea%b8%b0-%eb%8a%98%ec%97%88%eb%8b%a4%eb%a9%b4-%ec%95%94-%ec%8b%a0%ed%98%b8%ec%9d%bc%ea%b9%8c-%eb%a0%88%ec%a0%9c%eb%a5%b4-%ed%8a%b8%eb%a0%90\/","title":{"rendered":"Could Suddenly Developing More Age Spots Be a Sign of Cancer? Causes and Symptoms of the Leser-Tr\u00e9lat Syndrome"},"content":{"rendered":"<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"549\" src=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-1024x549.png\" alt=\"\" class=\"wp-image-927\" srcset=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-1024x549.png 1024w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-300x161.png 300w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-768x412.png 768w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-1536x823.png 1536w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-2048x1098.png 2048w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-18x10.png 18w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-440x236.png 440w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac01\ud654\uc99d-680x364.png 680w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>There are some skin changes that can appear suddenly, even in younger people. <\/p>\n\n\n\n<p>In particular, if skin lesions that usually occur in older adults suddenly appear in large numbers over a short period of time, <\/p>\n\n\n\n<p>it is important to find out the cause. <\/p>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0);color:#cf2e2e\" class=\"has-inline-color\">This is because certain skin changes can, in rare cases, be a sign associated with an underlying malignant tumor in the body.<\/mark><\/strong><\/p>\n\n\n\n<p>Our bodies can develop various types of skin moles and pigmented lesions. <\/p>\n\n\n\n<p>Some of these may be related to skin cancer, <\/p>\n\n\n\n<p>Certain types of skin lesions can sometimes appear as a sign of an internal cancer. <\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"549\" src=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-1024x549.png\" alt=\"\" class=\"wp-image-928\" srcset=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-1024x549.png 1024w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-300x161.png 300w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-768x412.png 768w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-1536x823.png 1536w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-2048x1098.png 2048w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-18x10.png 18w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-440x236.png 440w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uac80\ubc84\uc12f-680x364.png 680w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong>One such phenomenon is <mark style=\"background-color:rgba(0, 0, 0, 0);color:#cf2e2e\" class=\"has-inline-color\">The Leser-Tr\u00e9lat Sign (Leser-Tr\u00e9lat Syndrome)<\/mark>is.<\/strong><\/p>\n<\/blockquote>\n\n\n\n<p>To understand the Leser-Tr\u00e9lat sign, it is first necessary to understand the difference between age spots and seborrheic keratoses, which commonly appear with aging.<\/p>\n\n\n\n<p>Seborrheic keratosis is medically classified as a type of benign skin tumor. <\/p>\n\n\n\n<p>It commonly occurs with aging, <\/p>\n\n\n\n<p>The surface of these lesions is often uneven and rough, and they commonly appear brown or black in color. <\/p>\n\n\n\n<p>The lesions have well-defined borders and a raised surface, so they are sometimes mistaken for warts. However, they are a different type of skin lesion from warts.<\/p>\n\n\n\n<p>In contrast, solar lentigines are skin lesions that are generally flat and have relatively uniform pigmentation. <\/p>\n\n\n\n<p>Unlike solar lentigines, seborrheic keratoses may have a thick, rough surface and an irregular appearance. <\/p>\n\n\n\n<p>These skin lesions may also be found on the face, scalp, and other areas of the body.<\/p>\n\n\n\n<p>Because seborrheic keratosis is found much more commonly in older adults than in younger people, <\/p>\n\n\n\n<p>It is often considered one of the skin changes associated with aging. Although ultraviolet (UV) exposure and genetic factors may be related, the exact cause has not been fully established. <\/p>\n\n\n\n<p>The exact cause of its development has not yet been fully understood.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"549\" src=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-1024x549.png\" alt=\"\" class=\"wp-image-929\" srcset=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-1024x549.png 1024w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-300x161.png 300w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-768x412.png 768w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-1536x823.png 1536w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-2048x1098.png 2048w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-18x10.png 18w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-440x236.png 440w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654-680x364.png 680w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0);color:#cf2e2e\" class=\"has-inline-color\">What if multiple seborrheic keratoses appear suddenly over a short period of time?<\/mark><\/strong><\/p>\n<\/blockquote>\n\n\n\n<p>A rapid increase in seborrheic keratoses over a short period of time, or the sudden appearance of multiple lesions at the same time, is <\/p>\n\n\n\n<p>This phenomenon is called the Leser-Tr\u00e9lat sign. <\/p>\n\n\n\n<p>This sign can appear on various parts of the body, including the upper body such as the back, and may sometimes be accompanied by itching.<\/p>\n\n\n\n<p>The Leser-Tr\u00e9lat sign is a phenomenon that was first described in the late 19th century. <\/p>\n\n\n\n<p>Since then, an association between the sudden increase of seborrheic keratoses and internal malignant tumors has been reported. <\/p>\n\n\n\n<p>In particular, cases associated with gastrointestinal cancers such as stomach cancer, colon cancer, and rectal cancer have been reported, <\/p>\n\n\n\n<p>An association has also been reported with other malignant tumors, including lymphoproliferative neoplasms.<\/p>\n\n\n\n<p>Cancer cells can release various biological substances, <\/p>\n\n\n\n<p>These substances can sometimes affect other tissues in the body, including the skin. <\/p>\n\n\n\n<p>Various physical symptoms and skin changes associated with cancer can be explained within the category of paraneoplastic syndromes. <\/p>\n\n\n\n<p>The Leser-Tr\u00e9lat sign has also been studied in this context.<\/p>\n\n\n\n<p>However, whether this sign is a highly reliable indicator that can accurately predict cancer remains a subject of debate. <\/p>\n\n\n\n<p>Because seborrheic keratosis itself is very common with aging, <\/p>\n\n\n\n<p>It should also be considered that the skin lesions and cancer may have appeared at the same time purely by coincidence.<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#7bdcb5\" class=\"has-inline-color\">Therefore, a sudden increase in seborrheic keratoses does not necessarily mean that cancer is present. <\/mark><\/strong><\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"549\" src=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-1024x549.png\" alt=\"\" class=\"wp-image-930\" srcset=\"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-1024x549.png 1024w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-300x161.png 300w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-768x412.png 768w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-1536x823.png 1536w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-2048x1098.png 2048w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-18x10.png 18w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-440x236.png 440w, https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\uc554\uc138\ud3ec-680x364.png 680w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>However, if skin lesions develop in an unusually large number over a short period of time or change rapidly, <\/p>\n\n\n\n<p>It is advisable not to dismiss such changes lightly and to have them evaluated by a healthcare professional.<\/p>\n\n\n\n<p>In particular, when sudden skin changes occur, it is advisable to consult a dermatologist to evaluate the characteristics of the lesions. <\/p>\n\n\n\n<p>Whether additional tests are needed should be determined by considering a person's age, overall health condition, accompanying symptoms, and individual risk factors.<\/p>\n\n\n\n<p> Cancer screening is also important to perform according to an individual's age and risk factors.<\/p>\n\n\n\n<p>However, although the Leser-Tr\u00e9lat sign does not necessarily mean that cancer is present, <\/p>\n\n\n\n<p><strong><mark style=\"background-color:#fcb900\" class=\"has-inline-color\">However, sudden and unusual changes in the skin should not be ignored. <\/mark><\/strong><\/p>\n\n\n\n<p>Paying close attention to changes in your skin and seeking medical evaluation when necessary can help protect your health.<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\uc80a\uc740 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[&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":929,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[24],"tags":[],"class_list":["post-926","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-primary-health-care-provider"],"jetpack_featured_media_url":"https:\/\/kdoctorinterview.com\/wp-content\/uploads\/2026\/10\/\ub178\ud654.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/posts\/926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/comments?post=926"}],"version-history":[{"count":1,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/posts\/926\/revisions"}],"predecessor-version":[{"id":931,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/posts\/926\/revisions\/931"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/media\/929"}],"wp:attachment":[{"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/media?parent=926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/categories?post=926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kdoctorinterview.com\/en\/wp-json\/wp\/v2\/tags?post=926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}